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Senescence from G2 arrest, revisited
Senescence was classically defined as an irreversible cell cycle arrest in G1 phase (G1 exit) triggered by eroded telomeres in aged primary cells. The molecular basis of this G1 arrest is thought to be due to a DNA damage response, resulting in accumulation of the cyclin dependent kinase (Cdk) inhib...
Tallennettuna:
| Julkaisussa: | Cell Cycle |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Taylor & Francis
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353294/ https://ncbi.nlm.nih.gov/pubmed/25564883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2014.1000134 |
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