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Senescence from G2 arrest, revisited

Senescence was classically defined as an irreversible cell cycle arrest in G1 phase (G1 exit) triggered by eroded telomeres in aged primary cells. The molecular basis of this G1 arrest is thought to be due to a DNA damage response, resulting in accumulation of the cyclin dependent kinase (Cdk) inhib...

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Dades bibliogràfiques
Publicat a:Cell Cycle
Autors principals: Gire, Véronique, Dulić, Vjekoslav
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353294/
https://ncbi.nlm.nih.gov/pubmed/25564883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2014.1000134
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