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Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier
Mucopolysaccharidosis type VII is a lysosomal storage disorder resulting from inherited deficiency of β-glucuronidase (GUS). Mucopolysaccharidosis type VII is characterized by glycosaminoglycan storage in most tissues, including brain. In these disorders, enzyme delivery across the blood-brain barri...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC515112/ https://ncbi.nlm.nih.gov/pubmed/15314220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405042101 |
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