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Singular role for T-BET(+)CXCR3(+) regulatory T cells in protection from autoimmune diabetes

Foxp3(+) regulatory T (Treg) cells are crucial for restraining inflammation in a variety of autoimmune diseases, including type 1 diabetes (T1D). However, the transcriptional and functional phenotypes of Treg cells within the pancreatic lesion remain poorly understood. Here we characterized pancreas...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tan, Tze Guan, Mathis, Diane, Benoist, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150376/
https://ncbi.nlm.nih.gov/pubmed/27872297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616710113
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