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Singular role for T-BET(+)CXCR3(+) regulatory T cells in protection from autoimmune diabetes
Foxp3(+) regulatory T (Treg) cells are crucial for restraining inflammation in a variety of autoimmune diseases, including type 1 diabetes (T1D). However, the transcriptional and functional phenotypes of Treg cells within the pancreatic lesion remain poorly understood. Here we characterized pancreas...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5150376/ https://ncbi.nlm.nih.gov/pubmed/27872297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616710113 |
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