iRhom2 regulates cell surface expression of CSF1R and non-steady state myelopoiesis in mice

The colony stimulating factor 1 receptor (CSF1R) functions as the major receptor for macrophage colony stimulating factor (CSF1) with crucial roles in regulating myelopoeisis. CSF1R can be proteolytically released from the cell surface by A disintegrin and metalloprotease 17 (ADAM17). Here we identi...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Qing, Xiaoping, Rogers, Lindsay, Mortha, Arthur, Lavin, Yonit, Redecha, Patricia, Issuree, Priya D., Maretzky, Thorsten, Merad, Miriam, McIlwain, David, Mak, Tak W., Overall, Christopher M., Blobel, Carl P., Salmon, Jane E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149455/
https://ncbi.nlm.nih.gov/pubmed/27601030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646482
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