ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1)

The metalloprotease ADAM17 (a disintegrin and metalloprotease 17) is a key regulator of tumor necrosis factor α (TNFα), interleukin 6 receptor (IL-6R), and epidermal growth factor receptor (EGFR) signaling. ADAM17 maturation and function depend on the seven-membrane–spanning inactive rhomboid-like p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Weskamp, Gisela, Tüshaus, Johanna, Li, Daniel, Feederle, Regina, Maretzky, Thorsten, Swendemann, Steven, Falck-Pedersen, Erik, McIlwain, David R., Mak, Tak W., Salmon, Jane E., Lichtenthaler, Stefan F., Blobel, Carl P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Protein Synthesis and Degradation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105298/
https://ncbi.nlm.nih.gov/pubmed/32060096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011136
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg