ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1)

The metalloprotease ADAM17 (a disintegrin and metalloprotease 17) is a key regulator of tumor necrosis factor α (TNFα), interleukin 6 receptor (IL-6R), and epidermal growth factor receptor (EGFR) signaling. ADAM17 maturation and function depend on the seven-membrane–spanning inactive rhomboid-like p...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Weskamp, Gisela, Tüshaus, Johanna, Li, Daniel, Feederle, Regina, Maretzky, Thorsten, Swendemann, Steven, Falck-Pedersen, Erik, McIlwain, David R., Mak, Tak W., Salmon, Jane E., Lichtenthaler, Stefan F., Blobel, Carl P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2020
Teme:
Protein Synthesis and Degradation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105298/
https://ncbi.nlm.nih.gov/pubmed/32060096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011136
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki