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A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila

The CCR4–NOT complex is the major enzyme catalyzing mRNA deadenylation in Saccharomyces cerevisiae. We have identified homologs for almost all subunits of this complex in the Drosophila genome. Biochemical fractionation showed that the two likely catalytic subunits, CCR4 and CAF1, were associated wi...

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Bibliografiske detaljer
Main Authors: Temme, Claudia, Zaessinger, Sophie, Meyer, Sylke, Simonelig, Martine, Wahle, Elmar
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC514940/
https://ncbi.nlm.nih.gov/pubmed/15215893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600273
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