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A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila

The CCR4–NOT complex is the major enzyme catalyzing mRNA deadenylation in Saccharomyces cerevisiae. We have identified homologs for almost all subunits of this complex in the Drosophila genome. Biochemical fractionation showed that the two likely catalytic subunits, CCR4 and CAF1, were associated wi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Temme, Claudia, Zaessinger, Sophie, Meyer, Sylke, Simonelig, Martine, Wahle, Elmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC514940/
https://ncbi.nlm.nih.gov/pubmed/15215893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600273
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