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A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila

The CCR4–NOT complex is the major enzyme catalyzing mRNA deadenylation in Saccharomyces cerevisiae. We have identified homologs for almost all subunits of this complex in the Drosophila genome. Biochemical fractionation showed that the two likely catalytic subunits, CCR4 and CAF1, were associated wi...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Temme, Claudia, Zaessinger, Sophie, Meyer, Sylke, Simonelig, Martine, Wahle, Elmar
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514940/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15215893/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600273
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