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Deadenylation of mRNA by the CCR4–NOT complex in Drosophila: molecular and developmental aspects

Controlled shortening of the poly(A) tail of mRNAs is the first step in eukaryotic mRNA decay and can also be used for translational inactivation of mRNAs. The CCR4–NOT complex is the most important among a small number of deadenylases, enzymes catalyzing poly(A) tail shortening. Rates of poly(A) sh...

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Bibliographic Details
Main Authors: Temme, Claudia, Simonelig, Martine, Wahle, Elmar
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033318/
https://ncbi.nlm.nih.gov/pubmed/24904643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00143
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