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Deadenylation of mRNA by the CCR4–NOT complex in Drosophila: molecular and developmental aspects

Controlled shortening of the poly(A) tail of mRNAs is the first step in eukaryotic mRNA decay and can also be used for translational inactivation of mRNAs. The CCR4–NOT complex is the most important among a small number of deadenylases, enzymes catalyzing poly(A) tail shortening. Rates of poly(A) sh...

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Hlavní autoři: Temme, Claudia, Simonelig, Martine, Wahle, Elmar
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033318/
https://ncbi.nlm.nih.gov/pubmed/24904643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00143
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