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Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5’-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway

Schistosoma mansoni do not have de novo purine pathways and rely on purine salvage for their purine supply. It has been demonstrated that, unlike humans, the S. mansoni is able to produce adenine directly from adenosine, although the enzyme responsible for this activity was unknown. In the present w...

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Dades bibliogràfiques
Publicat a:PLoS Negl Trop Dis
Autors principals: Torini, Juliana Roberta, Brandão-Neto, José, DeMarco, Ricardo, Pereira, Humberto D'Muniz
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147791/
https://ncbi.nlm.nih.gov/pubmed/27935959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005178
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