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Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5’-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway

Schistosoma mansoni do not have de novo purine pathways and rely on purine salvage for their purine supply. It has been demonstrated that, unlike humans, the S. mansoni is able to produce adenine directly from adenosine, although the enzyme responsible for this activity was unknown. In the present w...

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Podrobná bibliografie
Vydáno v:PLoS Negl Trop Dis
Hlavní autoři: Torini, Juliana Roberta, Brandão-Neto, José, DeMarco, Ricardo, Pereira, Humberto D'Muniz
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147791/
https://ncbi.nlm.nih.gov/pubmed/27935959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005178
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