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Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate

Schistosomes are blood flukes which cause schistosomiasis, a disease affecting approximately 200 million people worldwide. Along with several other important human parasites including trypanosomes and Plasmodium, schistosomes lack the de novo pathway for purine synthesis and depend exclusively on th...

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Detalhes bibliográficos
Main Authors: D’Muniz Pereira, Humberto, Oliva, Glaucius, Garratt, Richard Charles
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004257/
https://ncbi.nlm.nih.gov/pubmed/21169694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0909049510027718
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