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Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5’-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway

Schistosoma mansoni do not have de novo purine pathways and rely on purine salvage for their purine supply. It has been demonstrated that, unlike humans, the S. mansoni is able to produce adenine directly from adenosine, although the enzyme responsible for this activity was unknown. In the present w...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Torini, Juliana Roberta, Brandão-Neto, José, DeMarco, Ricardo, Pereira, Humberto D'Muniz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147791/
https://ncbi.nlm.nih.gov/pubmed/27935959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005178
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