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Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5’-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway

Schistosoma mansoni do not have de novo purine pathways and rely on purine salvage for their purine supply. It has been demonstrated that, unlike humans, the S. mansoni is able to produce adenine directly from adenosine, although the enzyme responsible for this activity was unknown. In the present w...

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Dettagli Bibliografici
Pubblicato in:PLoS Negl Trop Dis
Autori principali: Torini, Juliana Roberta, Brandão-Neto, José, DeMarco, Ricardo, Pereira, Humberto D'Muniz
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147791/
https://ncbi.nlm.nih.gov/pubmed/27935959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005178
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