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Regulator of G-protein signalling and GoLoco proteins suppress TRPC4 channel function via acting at Gα(i/o)

Transient receptor potential canonical 4 (TRPC4) forms nonselective cation channels implicated in the regulation of diverse physiological functions. Previously, TRPC4 was shown to be activated by the G(i/o) subgroup of heterotrimeric G-proteins involving Gα(i/o), rather than Gβγ, subunits. Because t...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Jeon, Jae-Pyo, Thakur, Dhananjay P., Tian, Jin-bin, So, Insuk, Zhu, Michael X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146954/
https://ncbi.nlm.nih.gov/pubmed/26987813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160214
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