A Point Mutation to Gα(i) Selectively Blocks GoLoco Motif Binding: DIRECT EVIDENCE FOR Gα·GoLoco COMPLEXES IN MITOTIC SPINDLE DYNAMICS

Heterotrimeric G-protein Gα subunits and GoLoco motif proteins are key members of a conserved set of regulatory proteins that influence invertebrate asymmetric cell division and vertebrate neuroepithelium and epithelial progenitor differentiation. GoLoco motif proteins bind selectively to the inhibi...

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Detalhes bibliográficos
Main Authors: Willard, Francis S., Zheng, Zhen, Guo, Juan, Digby, Gregory J., Kimple, Adam J., Conley, Jason M., Johnston, Christopher A., Bosch, Dustin, Willard, Melinda D., Watts, Val J., Lambert, Nevin A., Ikeda, Stephen R., Du, Quansheng, Siderovski, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605979/
https://ncbi.nlm.nih.gov/pubmed/18984596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804936200
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