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A Point Mutation to Gα(i) Selectively Blocks GoLoco Motif Binding: DIRECT EVIDENCE FOR Gα·GoLoco COMPLEXES IN MITOTIC SPINDLE DYNAMICS

Heterotrimeric G-protein Gα subunits and GoLoco motif proteins are key members of a conserved set of regulatory proteins that influence invertebrate asymmetric cell division and vertebrate neuroepithelium and epithelial progenitor differentiation. GoLoco motif proteins bind selectively to the inhibi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Willard, Francis S., Zheng, Zhen, Guo, Juan, Digby, Gregory J., Kimple, Adam J., Conley, Jason M., Johnston, Christopher A., Bosch, Dustin, Willard, Melinda D., Watts, Val J., Lambert, Nevin A., Ikeda, Stephen R., Du, Quansheng, Siderovski, David P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605979/
https://ncbi.nlm.nih.gov/pubmed/18984596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804936200
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