Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.

GoLoco ('Galpha(i/o)-Loco' interaction) motif proteins have recently been identified as novel GDIs (guanine nucleotide dissociation inhibitors) for heterotrimeric G-protein alpha subunits. G18 is a member of the mammalian GoLoco-motif gene family and was uncovered by analyses of human and...

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Main Authors: Kimple, Randall J, Willard, Francis S, Hains, Melinda D, Jones, Miller B, Nweke, Gift K, Siderovski, David P
Formato: Artigo
Idioma:Inglês
Publicado: 2004
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224015/
https://ncbi.nlm.nih.gov/pubmed/14656218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031686
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