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GoLoco motif proteins binding to Gα(i1): insights from molecular simulations

Molecular dynamics simulations, computational alanine scanning and sequence analysis were used to investigate the structural properties of the Gα(i1)/GoLoco peptide complex. Using these methodologies, binding of the GoLoco motif peptide to the Gα(i1) subunit was found to restrict the relative moveme...

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Detalhes bibliográficos
Autor principal: Khafizov, Kamil
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847169/
https://ncbi.nlm.nih.gov/pubmed/19437048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-009-0516-z
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