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Mode of interaction of the Gαo subunit of heterotrimeric G proteins with the GoLoco1 motif of Drosophila Pins is determined by guanine nucleotides

Drosophila GoLoco motif-containing protein Pins is unusual in its highly efficient interaction with both GDP- and the GTP-loaded forms of the α-subunit of the heterotrimeric Go protein. We analysed the interactions of Gαo in its two nucleotide forms with GoLoco1–the first of the three GoLoco domains...

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Publicat a:Biosci Rep
Autors principals: Lüchtenborg, Anne-Marie, Purvanov, Vladimir, Melnik, Bogdan S., Becker, Simon, Katanaev, Vladimir L.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660580/
https://ncbi.nlm.nih.gov/pubmed/26487707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150201
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