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TAK1 Regulates the Nrf2 Antioxidant System Through Modulating p62/SQSTM1
Aims: Nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2) is the master transcriptional regulator of antioxidant gene expression. On increased oxidative stress, an adaptor for Nrf2 degradation, Kelch-like ECH-associated protein 1 (Keap1), is directly modulated by oxidants in the cytoplasm, wh...
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| Publié dans: | Antioxid Redox Signal |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Mary Ann Liebert, Inc.
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5144887/ https://ncbi.nlm.nih.gov/pubmed/27245349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6663 |
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