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Nuclear Lamins and Progerin Are Dispensable for Antioxidant Nrf2 Response to Arsenic and Cadmium

Lamins are important constituents of the nuclear inner membrane and provide a platform for transcription factors and chromatin. Progerin, a C-terminal truncated lamin A mutant, causes premature aging termed Hutchinson-Gilford Progeria Syndrome (HGPS). Oxidative stress appears to be involved in the p...

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Détails bibliographiques
Publié dans:Cell Signal
Auteurs principaux: Hashimoto, Kazunori, Majumdar, Rima, Tsuji, Yoshiaki
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377904/
https://ncbi.nlm.nih.gov/pubmed/28229933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.02.012
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