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Nuclear Lamins and Progerin Are Dispensable for Antioxidant Nrf2 Response to Arsenic and Cadmium
Lamins are important constituents of the nuclear inner membrane and provide a platform for transcription factors and chromatin. Progerin, a C-terminal truncated lamin A mutant, causes premature aging termed Hutchinson-Gilford Progeria Syndrome (HGPS). Oxidative stress appears to be involved in the p...
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| Publié dans: | Cell Signal |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5377904/ https://ncbi.nlm.nih.gov/pubmed/28229933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.02.012 |
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