Long Isoforms of NRF1 Contribute to Arsenic-Induced Antioxidant Response in Human Keratinocytes

BACKGROUND: Human exposure to inorganic arsenic (iAs), a potent oxidative stressor, causes various dermal disorders, including hyperkeratosis and skin cancer. Nuclear factor–erythroid 2–related factor 1 (NRF1, also called NFE2L1) plays a critical role in regulating the expression of many antioxidant...

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Autori principali: Zhao, Rui, Hou, Yongyong, Xue, Peng, Woods, Courtney G., Fu, Jingqi, Feng, Bo, Guan, Dawei, Sun, Guifan, Chan, Jefferson Y., Waalkes, Michael P., Andersen, Melvin E., Pi, Jingbo
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Institute of Environmental Health Sciences 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018500/
https://ncbi.nlm.nih.gov/pubmed/20805060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1002304
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