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TAK1 regulates Paneth cell integrity partly through blocking necroptosis

Paneth cells reside at the base of crypts of the small intestine and secrete antimicrobial factors to control gut microbiota. Paneth cell loss is observed in the chronically inflamed intestine, which is often associated with increased reactive oxygen species (ROS). However, the relationship between...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Simmons, A N, Kajino-Sakamoto, R, Ninomiya-Tsuji, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855677/
https://ncbi.nlm.nih.gov/pubmed/27077812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.98
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