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TAK1 regulates hepatic lipid homeostasis through SREBP

Sterol regulatory element-binding proteins (SREBPs) are key transcription factors regulating cholesterol and fatty acid biosynthesis. SREBP activity is tightly regulated to maintain lipid homeostasis, and is modulated upon extracellular stimuli such as growth factors. While the homeostatic SREBP reg...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Morioka, Sho, Sai, Kazuhito, Omori, Emily, Ikeda, Yuka, Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956508/
https://ncbi.nlm.nih.gov/pubmed/26973245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.453
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