TAK1 regulates Paneth cell integrity partly through blocking necroptosis

Paneth cells reside at the base of crypts of the small intestine and secrete antimicrobial factors to control gut microbiota. Paneth cell loss is observed in the chronically inflamed intestine, which is often associated with increased reactive oxygen species (ROS). However, the relationship between...

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Опубликовано в: :Cell Death Dis
Главные авторы: Simmons, A N, Kajino-Sakamoto, R, Ninomiya-Tsuji, J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855677/
https://ncbi.nlm.nih.gov/pubmed/27077812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.98
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