STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-λ but not by interferon-α

Interferon-α (IFN-α) and IFN-λ are structurally distinct cytokines that bind to different receptors, but induce expression of similar sets of genes through Janus kinase (JAK)-signal transducers and activators of transcription (STAT) pathways. The difference between IFN-α and IFN-λ signaling remains...

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Publicado no:Sci Rep
Main Authors: Yamauchi, Shota, Takeuchi, Kenji, Chihara, Kazuyasu, Honjoh, Chisato, Kato, Yuji, Yoshiki, Hatsumi, Hotta, Hak, Sada, Kiyonao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144079/
https://ncbi.nlm.nih.gov/pubmed/27929099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38336
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