HCV NS5A Protein Containing Potential Ligands for Both Src Homology 2 and 3 Domains Enhances Autophosphorylation of Src Family Kinase Fyn in B Cells

Hepatitis C virus (HCV) infects B lymphocytes and induces mixed cryoglobulinemia and B cell non-Hodgkin's lymphoma. The molecular mechanism for the pathogenesis of HCV infection-mediated B cell disorders remains obscure. To identify the possible role for HCV nonstructural 5A (NS5A) protein in B...

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Main Authors: Nakashima, Kenji, Takeuchi, Kenji, Chihara, Kazuyasu, Horiguchi, Tomoko, Sun, Xuedong, Deng, Lin, Shoji, Ikuo, Hotta, Hak, Sada, Kiyonao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473057/
https://ncbi.nlm.nih.gov/pubmed/23077515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046634
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