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STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-λ but not by interferon-α
Interferon-α (IFN-α) and IFN-λ are structurally distinct cytokines that bind to different receptors, but induce expression of similar sets of genes through Janus kinase (JAK)-signal transducers and activators of transcription (STAT) pathways. The difference between IFN-α and IFN-λ signaling remains...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5144079/ https://ncbi.nlm.nih.gov/pubmed/27929099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38336 |
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