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Hepatitis C Virus Particle Assembly Involves Phosphorylation of NS5A by the c-Abl Tyrosine Kinase

Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) is thought to regulate the replication of viral RNA and the assembly of virus particles in a serine/threonine phosphorylation-dependent manner. However, the host kinases that phosphorylate NS5A have not been fully identified. Here, we show that...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Yamauchi, Shota, Takeuchi, Kenji, Chihara, Kazuyasu, Sun, Xuedong, Honjoh, Chisato, Yoshiki, Hatsumi, Hotta, Hak, Sada, Kiyonao
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571941/
https://ncbi.nlm.nih.gov/pubmed/26203192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.666859
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