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Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation
We previously reported early and extensive loss of astrocytic connexin 43 (Cx43) in acute demyelinating lesions of multiple sclerosis (MS) patients. Because it is widely accepted that autoimmune T cells initiate MS lesions, we hypothesized that infiltrating T cells affect Cx43 expression in astrocyt...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5143974/ https://ncbi.nlm.nih.gov/pubmed/27929069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38387 |
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