Downregulation of Neuronal and Dendritic Connexin36-Made Electrical Synapses Without Glutamatergic Axon Terminals in Spinal Anterior Horn Cells From the Early Stage of Amyotrophic Lateral Sclerosis

Connexin36 (Cx36) forms gap junctions between neurons, which are called electrical synapses, enabling adjacent neurons to communicate directly. The participation of chemical synapses in neurodegeneration in amyotrophic lateral sclerosis (ALS) has long been indicated, but it remains unclear whether e...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Kobayakawa, Yuko, Masaki, Katsuhisa, Yamasaki, Ryo, Shiraishi, Wataru, Hayashida, Shotaro, Hayashi, Shintaro, Okamoto, Koichi, Matsushita, Takuya, Kira, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279874/
https://ncbi.nlm.nih.gov/pubmed/30546295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00894
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