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Multi-Domain Terpenoid Cyclase Architecture and Prospects for Proximity in Bifunctional Catalysis

Crystal structures of terpenoid cyclases reveal assemblies of three basic domains designated α, β, and γ. While the biosynthesis of cyclic monoterpenes (C(10)) and sesquiterpenes (C(15)) most often involves enzymes with α or αβ domain architecture, the biosynthesis of cyclic diterpenes (C(20)), sest...

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Bibliografske podrobnosti
izdano v:Curr Opin Struct Biol
Main Authors: Chen, Mengbin, Harris, Golda G., Pemberton, Travis A., Christianson, David W.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143216/
https://ncbi.nlm.nih.gov/pubmed/27285057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.05.010
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