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Multi-Domain Terpenoid Cyclase Architecture and Prospects for Proximity in Bifunctional Catalysis

Crystal structures of terpenoid cyclases reveal assemblies of three basic domains designated α, β, and γ. While the biosynthesis of cyclic monoterpenes (C(10)) and sesquiterpenes (C(15)) most often involves enzymes with α or αβ domain architecture, the biosynthesis of cyclic diterpenes (C(20)), sest...

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Detalhes bibliográficos
Publicado no:Curr Opin Struct Biol
Main Authors: Chen, Mengbin, Harris, Golda G., Pemberton, Travis A., Christianson, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143216/
https://ncbi.nlm.nih.gov/pubmed/27285057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.05.010
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