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General Base-General Acid Catalysis by Terpenoid Cyclases()

Terpenoid cyclases catalyze the most complex reactions in biology, in that more than half of the substrate carbon atoms often undergo changes in bonding during the course of a multistep cyclization cascade that proceeds through multiple carbocation intermediates. Many cyclization mechanisms require...

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Detalhes bibliográficos
Publicado no:J Antibiot (Tokyo)
Main Authors: Pemberton, Travis A., Christianson, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963284/
https://ncbi.nlm.nih.gov/pubmed/27072285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2016.39
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