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Crystal Structure of Cucumene Synthase, a Terpenoid Cyclase that Generates a Linear Triquinane Sesquiterpene

Linear triquinanes are sesquiterpene natural products with hydrocarbon skeletons consisting of three fused 5-membered rings. Importantly, several of these compounds exhibit useful anti-cancer, anti-inflammatory, and antibiotic properties. However, linear triquinanes pose significant challenges to or...

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Vydáno v:Biochemistry
Hlavní autoři: Blank, Patrick N., Pemberton, Travis A., Chow, Jeng-Yeong, Poulter, C. Dale, Christianson, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240786/
https://ncbi.nlm.nih.gov/pubmed/30346736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00899
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