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Computational-guided discovery and characterization of a sesquiterpene synthase from Streptomyces clavuligerus

Terpenoids are a large structurally diverse group of natural products with an array of functions in their hosts. The large amount of genomic information from recent sequencing efforts provides opportunities and challenges for the functional assignment of terpene synthases that construct the carbon s...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Chow, Jeng-Yeong, Tian, Bo-Xue, Ramamoorthy, Gurusankar, Hillerich, Brandan S., Seidel, Ronald D., Almo, Steven C., Jacobson, Matthew P., Poulter, C. Dale
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426440/
https://ncbi.nlm.nih.gov/pubmed/25901324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505127112
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