Computational-guided discovery and characterization of a sesquiterpene synthase from Streptomyces clavuligerus

Terpenoids are a large structurally diverse group of natural products with an array of functions in their hosts. The large amount of genomic information from recent sequencing efforts provides opportunities and challenges for the functional assignment of terpene synthases that construct the carbon s...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Chow, Jeng-Yeong, Tian, Bo-Xue, Ramamoorthy, Gurusankar, Hillerich, Brandan S., Seidel, Ronald D., Almo, Steven C., Jacobson, Matthew P., Poulter, C. Dale
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426440/
https://ncbi.nlm.nih.gov/pubmed/25901324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505127112
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