Exploring the Influence of Domain Architecture on the Catalytic Function of Diterpene Synthases

Terpenoid synthases catalyze isoprenoid cyclization reactions underlying the generation of more than 80,000 natural products. Such dramatic chemodiversity belies the fact that these enzymes generally consist of only three domain folds designated α, β, and γ. Catalysis by class I terpenoid synthases...

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Pubblicato in:Biochemistry
Autori principali: Pemberton, Travis A., Chen, Mengbin, Harris, Golda G., Chou, Wayne K. W., Duan, Lian, Köksal, Mustafa, Genshaft, Alex S, Cane, David E., Christianson, David W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474940/
https://ncbi.nlm.nih.gov/pubmed/28362483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00137
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