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Hyperoxia-induced p47(phox) activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P(1&2) signaling axis in lung endothelium
Hyperoxia-induced lung injury adversely affects ICU patients and neonates on ventilator assisted breathing. The underlying culprit appears to be reactive oxygen species (ROS)-induced lung damage. The major contributor of hyperoxia-induced ROS is activation of the multiprotein enzyme complex NADPH ox...
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| 出版年: | Am J Physiol Lung Cell Mol Physiol |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142460/ https://ncbi.nlm.nih.gov/pubmed/27343196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00447.2015 |
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