Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium

Hepatocyte growth factor (HGF) signaling via c-Met is known to promote endothelial cell motility and angiogenesis. We have previously reported that HGF stimulates lamellipodia formation and motility of human lung microvascular endothelial cells (HLMVECs) via PI3K/Akt signal transduction and reactive...

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Foilsithe in:J Biol Chem
Main Authors: Fu, Panfeng, Ebenezer, David L., Berdyshev, Evgeny V., Bronova, Irina A., Shaaya, Mark, Harijith, Anantha, Natarajan, Viswanathan
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2016
Ábhair:
Signal Transduction
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207147/
https://ncbi.nlm.nih.gov/pubmed/27864331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.758946
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