Hyperoxia-induced p47(phox) activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P(1&2) signaling axis in lung endothelium

Hyperoxia-induced lung injury adversely affects ICU patients and neonates on ventilator assisted breathing. The underlying culprit appears to be reactive oxygen species (ROS)-induced lung damage. The major contributor of hyperoxia-induced ROS is activation of the multiprotein enzyme complex NADPH ox...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Harijith, Anantha, Pendyala, Srikanth, Ebenezer, David L., Ha, Alison W., Fu, Panfeng, Wang, Yue-Ting, Ma, Ke, Toth, Peter T., Berdyshev, Evgeny V., Kanteti, Prasad, Natarajan, Viswanathan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142460/
https://ncbi.nlm.nih.gov/pubmed/27343196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00447.2015
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