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Trafficking and function of the cystic fibrosis transmembrane conductance regulator: a complex network of posttranslational modifications

Posttranslational modifications add diversity to protein function. Throughout its life cycle, the cystic fibrosis transmembrane conductance regulator (CFTR) undergoes numerous covalent posttranslational modifications (PTMs), including glycosylation, ubiquitination, sumoylation, phosphorylation, and...

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Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: McClure, Michelle L., Barnes, Stephen, Brodsky, Jeffrey L., Sorscher, Eric J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142128/
https://ncbi.nlm.nih.gov/pubmed/27474090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00431.2015
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