Trafficking and function of the cystic fibrosis transmembrane conductance regulator: a complex network of posttranslational modifications

Posttranslational modifications add diversity to protein function. Throughout its life cycle, the cystic fibrosis transmembrane conductance regulator (CFTR) undergoes numerous covalent posttranslational modifications (PTMs), including glycosylation, ubiquitination, sumoylation, phosphorylation, and...

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Bibliographic Details
Published in:Am J Physiol Lung Cell Mol Physiol
Main Authors: McClure, Michelle L., Barnes, Stephen, Brodsky, Jeffrey L., Sorscher, Eric J.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142128/
https://ncbi.nlm.nih.gov/pubmed/27474090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00431.2015
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