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An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis

HD domain phosphohydrolase enzymes are characterized by a conserved set of histidine and aspartate residues that coordinate an active site metallocenter. Despite the important roles these enzymes play in nucleotide metabolism and signal transduction, few have been both biochemically and structurally...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Bridwell-Rabb, Jennifer, Kang, Gyunghoon, Zhong, Aoshu, Liu, Hung-wen, Drennan, Catherine L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137760/
https://ncbi.nlm.nih.gov/pubmed/27849620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613610113
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