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An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis
HD domain phosphohydrolase enzymes are characterized by a conserved set of histidine and aspartate residues that coordinate an active site metallocenter. Despite the important roles these enzymes play in nucleotide metabolism and signal transduction, few have been both biochemically and structurally...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137760/ https://ncbi.nlm.nih.gov/pubmed/27849620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613610113 |
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