Catalytic Conversion of Lipophilic Substrates by Phase constrained Enzymes in the Aqueous or in the Membrane Phase

Both soluble and membrane-bound enzymes can catalyze the conversion of lipophilic substrates. The precise substrate access path, with regard to phase, has however, until now relied on conjecture from enzyme structural data only (certainly giving credible and valuable hypotheses). Alternative methods...

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Pubblicato in:Sci Rep
Autori principali: Cebula, Marcus, Turan, Ilke Simsek, Sjödin, Birgitta, Thulasingam, Madhuranayaki, Brock, Joseph, Chmyrov, Volodymyr, Widengren, Jerker, Abe, Hiroshi, Mannervik, Bengt, Haeggström, Jesper Z., Rinaldo-Matthis, Agnes, Akkaya, Engin U., Morgenstern, Ralf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137027/
https://ncbi.nlm.nih.gov/pubmed/27917951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38316
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