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Imaging of intermittent lipid-receptor interactions reflects changes in live cell membranes upon agonist-receptor binding

Protein-lipid interactions in cellular membranes modulate central cellular functions, are often transient in character, but occur too intermittently to be readily observable. We introduce transient state imaging (TRAST), combining sensitive fluorescence detection of fluorophore markers with monitori...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tornmalm, Johan, Piguet, Joachim, Chmyrov, Volodymyr, Widengren, Jerker
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889430/
https://ncbi.nlm.nih.gov/pubmed/31792325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54625-w
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