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Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β

Cells of the immune system that reside in barrier epithelia provide a first line of defense against pathogens. Langerhans cells (LCs) and CD8(+) tissue-resident memory T cells (T(RM) cells) require active transforming growth factor-β1 (TGF-β) for epidermal residence. Here we found that integrins α(v...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Mohammed, Javed, Beura, Lalit K, Bobr, Aleh, Astry, Brian, Chicoine, Brian, Kashem, Sakeen W, Welty, Nathan E, Igyártó, Botond Z, Wijeyesinghe, Sathi, Thompson, Emily A, Matte, Catherine, Bartholin, Laurent, Kaplan, Alesia, Sheppard, Dean, Bridges, Alina G, Shlomchik, Warren D, Masopust, David, Kaplan, Daniel H
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135085/
https://ncbi.nlm.nih.gov/pubmed/26901152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3396
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