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Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β
Cells of the immune system that reside in barrier epithelia provide a first line of defense against pathogens. Langerhans cells (LCs) and CD8(+) tissue-resident memory T cells (T(RM) cells) require active transforming growth factor-β1 (TGF-β) for epidermal residence. Here we found that integrins α(v...
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| Publicado no: | Nat Immunol |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5135085/ https://ncbi.nlm.nih.gov/pubmed/26901152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3396 |
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