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Intravital mucosal imaging of CD8(+) resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory

CD8(+) T cell immunosurveillance dynamics influence the outcome of intracellular infections and cancer. Here we used two-photon intravital microscopy to visualize the responses of CD8(+) resident memory T cells (T(RM) cells) within the reproductive tracts of live female mice. We found that mucosal T...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Beura, Lalit K., Mitchell, Jason S., Thompson, Emily A., Schenkel, Jason M., Mohammed, Javed, Wijeyesinghe, Sathi, Fonseca, Raissa, Burbach, Brandon J., Hickman, Heather D., Vezys, Vaiva, Fife, Brian T., Masopust, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896323/
https://ncbi.nlm.nih.gov/pubmed/29311694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-017-0029-3
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