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Intravital mucosal imaging of CD8(+) resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory

CD8(+) T cell immunosurveillance dynamics influence the outcome of intracellular infections and cancer. Here we used two-photon intravital microscopy to visualize the responses of CD8(+) resident memory T cells (T(RM) cells) within the reproductive tracts of live female mice. We found that mucosal T...

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Bibliografiske detaljer
Udgivet i:Nat Immunol
Main Authors: Beura, Lalit K., Mitchell, Jason S., Thompson, Emily A., Schenkel, Jason M., Mohammed, Javed, Wijeyesinghe, Sathi, Fonseca, Raissa, Burbach, Brandon J., Hickman, Heather D., Vezys, Vaiva, Fife, Brian T., Masopust, David
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896323/
https://ncbi.nlm.nih.gov/pubmed/29311694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-017-0029-3
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