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Resident memory CD8 T cells trigger protective innate and adaptive immune responses

The pathogen recognition theory dictates that upon viral infection, the innate immune system first detects microbial products, and then responds by providing instructions to adaptive CD8 T cells. Here, we show in mice that resident memory CD8 T cells (T(RM)), non-recirculating cells located at commo...

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Bibliografiska uppgifter
I publikationen:Science
Huvudupphovsmän: Schenkel, Jason M., Fraser, Kathryn A., Beura, Lalit K., Pauken, Kristen E., Vezys, Vaiva, Masopust, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449618/
https://ncbi.nlm.nih.gov/pubmed/25170049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1254536
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