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Resident memory CD8 T cells trigger protective innate and adaptive immune responses

The pathogen recognition theory dictates that upon viral infection, the innate immune system first detects microbial products, and then responds by providing instructions to adaptive CD8 T cells. Here, we show in mice that resident memory CD8 T cells (T(RM)), non-recirculating cells located at commo...

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Détails bibliographiques
Publié dans:Science
Auteurs principaux: Schenkel, Jason M., Fraser, Kathryn A., Beura, Lalit K., Pauken, Kristen E., Vezys, Vaiva, Masopust, David
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449618/
https://ncbi.nlm.nih.gov/pubmed/25170049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1254536
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