Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β

Cells of the immune system that reside in barrier epithelia provide a first line of defense against pathogens. Langerhans cells (LCs) and CD8(+) tissue-resident memory T cells (T(RM) cells) require active transforming growth factor-β1 (TGF-β) for epidermal residence. Here we found that integrins α(v...

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Vydáno v:Nat Immunol
Hlavní autoři: Mohammed, Javed, Beura, Lalit K, Bobr, Aleh, Astry, Brian, Chicoine, Brian, Kashem, Sakeen W, Welty, Nathan E, Igyártó, Botond Z, Wijeyesinghe, Sathi, Thompson, Emily A, Matte, Catherine, Bartholin, Laurent, Kaplan, Alesia, Sheppard, Dean, Bridges, Alina G, Shlomchik, Warren D, Masopust, David, Kaplan, Daniel H
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135085/
https://ncbi.nlm.nih.gov/pubmed/26901152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3396
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